AureoGen

AureoGen is a research-based biotechnology company focused on the discovery and production of commercially and clinically important cyclic peptide-based drugs. AureoGen is developing a novel technology that will allow cost-effective optimization and production of cyclic peptide-based drugs through genetic engineering of the producer organisms, as an alternative to currently used complex and expensive synthetic chemistry methods. AureoGen's business is centered on generation intellectual property, through discovery of novel genes, drug molecules and organisms, as well as through development of novel technology, engineered organisms and compounds.

CeeTox, Inc.

CeeTox Inc. was founded in June of 2003 as a Contract Research Organization focused on in vitro toxicity screening of potential drug candidates and chemicals. CeeTox resides in 4000 square feet of state-of-the-art laboratory space in a thirteen million dollar facility that serves as an incubator for new biotech companies in the Kalamazoo , Michigan area. The scientists in CeeTox have a collective experience of more than 100 years in areas of cell culture, biochemistry, and toxicology. The team has analyzed more than 3000 new chemical entities and has repeatedly demonstrated the value of early in vitro toxicity data in the drug discovery process.

Jasper Clinical Research & Development

JCRD provides early-phase clinical studies of drug candidates and drug development consultation services.

Kalexsyn

Kalexsyn is a contract research company that provides medicinal chemistry support to drug discovery programs at pharmaceutical and biotech companies. Kalexsyn's staff is highly experienced, with each chemist having an average of 15 years of real experience in the pharmaceutical industry. Kalexsyn has expertise in organic synthesis, physical property modification, analog strategies, lead optimization, and diversification of compound collections.

Komodo Pharmaceutical Services, L.L.C.

The primary goal of Komodo Pharmaceutical Services, L.L.C. is the manufacture and distribution of CapTab™ capsules for use by clinical research operations in the pharmaceutical industry. This patented product is a tablet-shaped gelatin capsule, used to disguise research medications. Since the two-piece gelatin capsule is tablet-shaped, it can readily encapsulates solid dose medications of all sizes. Compared to other methods of disguising tablets for research, CapTab reduces the number of doses required for patients in clinical studies, lowers the cost of clinical studies, and significantly reduces the time required for completion of clinical trials. These advantages result in faster approval for new medications.

Michigan High Throughput Screening Center

We provide state-of-the-art High Throughput Screening technology to public research institutions and biotechnology companies to identify potential leads for drug discovery and develop chemical research tools to explore biochemical and metabolic pathways. We are members of the Michigan Core Technology Alliance, a consortium of research laboratories with the goal of developing technologically sophisticated core facilities to enhance life sciences research and product development throughout the State of Michigan.

Micromyx

Micromyx is a microbiology services company specializing in anti-infective discovery and development for the pharmaceutical, biotechnology, and animal health industries. Founded in 2004 by former pharmaceutical industry infectious disease scientists, Micromyx is a unique contract research organization that offers clients documented, top-of-the-line laboratory services from experts who have successfully gained FDA approval of new antibiotics.Micromyx will customize the relationship with each client. We can provide either stand-alone assay services to meet the client's specific needs, or we can establish a collaborative discovery program for exploratory projects.

MPI Research

MPI Research is a privately held Midwestern company that focuses on the nonclinical research needs of the pharmaceutical, biotech, chemical, agricultural and related industries. Our success is attributed to the mastery of effective teamwork and to being the very best in our field.

Nanovir

Nanovir is focused on the development of molecular strategies for fighting the sole cause of cervical cancer: human papillomavirus. HPV is the most prevalent sexually transmitted virus. Although best known for its role as the cause of cervical cancer, HPV is also the infectious agent that causes genital and other warts. Cervical cancer is the second leading cause of cancer deaths among women worldwide. Genital warts exceed genital herpes as a major contributor to doctor's visits.

NephRx

NephRx is a biotechnology company dedicated to the development of renal and gastrointestinal peptide-based therapeutics. The company's two lead molecules in development are treatments for 1) acute renal failure and 2) mucositis. The lead candidates are covered by issued and pending patents licensed by NephRx. Both candidates pre-clinical. Novel mechanisms of action have been characterized and, studies to clarify pharmacological properties are on-going. The company is open to the possibility of co-development relationships.

Perrigo

Based in Allegan , Michigan , U.S.A. , we are a leading global healthcare supplier and the world's largest manufacturer of the over-the-counter (OTC) pharmaceutical and nutritional products sold by food, drug, mass merchandise, dollar store and club store retailers under their own labels. Our products contain the same active ingredients as the advertised brand for less cost to the customer. On average, consumers experience the same relief by using our products in place of the advertised brand, while encountering significant savings.

PharmOptima

PharmOptima focuses on the mid to late phases of drug development between target identification and selection of lead compounds, helping clients select the best candidates to accelerate drug development and increase chances for clinical success. We also provide consultation and laboratory support for target selection and high throughput screening (HTS) assays. Our clients save money and time by selecting the best drug candidates and identifying potential problems early, before costly animal safety and first in man testing.

Pfizer

Pfizer Inc discovers, develops, manufactures, and markets leading prescription medicines for humans and animals and many of the world's best-known consumer brands. Our innovative, value-added products improve the quality of life of people around the world and help them enjoy longer, healthier, and more productive lives. The company has three business segments: health care, animal health and consumer health care.

ProNAi Therapeutics

ProNAi Therapeutics is a pre-clinical development-stage biopharmaceutical company based in the Southwest Michigan Innovation Center in Kalamazoo , Michigan . ProNAi is focused on bringing to market novel Nucleic Acid inhibitor (NAi) drugs to treat complex genetic disease, initially in cancer. ProNAi is currently proving NAi-based drug candidates in animals. The company intends to file its first INDs for prostate cancer and Non-Hodgkin's Lymphoma (NHL) in 2006.

Proteos

Proteos was founded in the summer of 2003 by a group of scientists in Kalamazoo , Michigan , who had been producing and qualifying proteins and peptides for nearly two decades in a large pharmaceutical company. Under the heading of Service, we offer customers input ranging from consultation on strategies covering all aspects of protein production and purification to Service or Research in providing crude, or pure proteins and peptides. Proteos provides a battery of analytical procedures to assure Quality of its products, including protein sequencing and mass spectroscopy. We can also aid in assay development, or application of given protocols as part of quality assurance. Proteos has now begun to produce Protein Products for sale, the first being recombinant human renin. Finally, Proteos intends to partner with large and small pharmaceutical and biotech companies, as well as with universities and government agencies to explore new protein therapeutic products that will add to our Intellectual Property.

Richard-Allan

Richard-Allan Scientific is a worldwide developer and producer of instruments and supplies for anatomical pathology and other key laboratory disciplines. With our headquarters located in Kalamazoo , Michigan , we operate manufacturing and sales facilities within the United States and Europe . Our organization consists of two Strategic Business Units; Richard-Allan Scientific and Microm International.

Stryker Orthopedics

Stryker Corporation is a leader in the worldwide orthopaedic market and is one of the world’s largest medical device companies.

zuChem

zuChem is a biotechnology company focused on the development and commercialization of novel manufacturing methods for the production of glycochemicals While the greatest long term need for such glycochemical compounds is by the pharmaceutical industry, the company is also exploiting the significant commercial opportunities for these compounds in the food ingredients and specialty chemical markets. zuChem's mission is to be the premier supplier of unique glycochemicals (sugar-like molecules) to the pharmaceutical and food ingredients industries, using proprietary technology to produce glycochemicals that are either extremely difficult or too expensive to manufacture via traditional synthetic methods.